Journal: bioRxiv

Article Title: Two distinct types of eye-head coupling in freely moving mice

doi: 10.1101/2020.02.20.957712

Figure Lengend Snippet: (A) Top: Head tilt was measured using the IMU sensor attached to the animal’s head. Eye positions were measured using the head-mounted camera system. Computational models were used to predict horizontal and vertical eye positions from head pitch and roll for each eye. Bottom: Measured (colored lines) and predicted (black lines) horizontal and vertical eye positions for both eyes. (B) Cross-validated explained variance along the horizontal (horiz.) and vertical (vert.) eye axes ( n = 47 recordings from 5 mice, 10 min each). Head tilt explained 86% variance in vertical but only 62% in horizontal eye position. Recordings for each eye axis pooled across eyes and mice. (C) Interocular correlation of the eye movements that were predictable by head pitch and roll (i.e. the predictions of independent models for the two eyes as shown in A). Strong negative correlation for horizontal eye movements indicates convergence and divergence across eyes. Blue arrows show horizontal convergence. Same data as in B. (D) Prediction errors for the eye position traces in A showed strong co-fluctuations in horizontal but not vertical eye direction. (E) Interocular correlation of the eye movements that were not predictable by head pitch and roll (i.e. the prediction errors of independent models for the two eyes as shown in D). There was a strong positive correlation for horizontal eye movements suggesting that conjugate eye movements occurred during head free behavior and were not explained by head tilt. Arrows show coupling for left eye rotating in nasal direction. Same data as in B.

Article Snippet: For the experiments in freely moving humans, eye position and head motion were recorded using a commercially-available head-mounted eye tracker with integrated IMU sensor (Tobii Pro Glasses 2, Tobii Pro, Sweden).

Techniques:

Journal: Journal of the Royal Society of Medicine

Article Title: A review of wearable technology in medicine

doi: 10.1177/0141076816663560

Figure Lengend Snippet: An overview of the available head-mounted display devices and their utilisation.

Article Snippet: Use in surgery A case series reported the use of a head-mounted display, MicroOptical™ (MicroOptical™ Corporation, USA), within orthopaedic surgery to view intraoperative fluoroscopy images during the procedure.

Techniques: Sterility, Imaging

Journal: Neurobiology of disease

Article Title: APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures

doi: 10.1016/j.nbd.2016.11.002

Figure Lengend Snippet: (A) Example EEG recording from P9 WT mouse showing little to no high amplitude activity. (Inset) Increased time scale of (A) at time 1. (B) Example EEG recording from P9 APC cKO animal showing multiple high amplitude EEG events. (Inset) Increased time scale of (B) at times 1 and 2. Note: Both (1) simple high amplitude spikes and (2) more complex high amplitude spikes followed by continued disruption of the EEG occur in APC cKO animals. (C) Image of a P12 mouse implanted with a radio-telemetry based EEG head mount. (D) Quantification of the frequency of high amplitude discharges in WT and APC cKO mice (*** p<0.001, 2 way ANOVA, WT: P9, n=3, P10, n=6, P11, n=6, P12, n=6; cKO: P9, n=3, P10, n=4, P11, n=6, P12, n=6). The peak of aberrant EEG activity at P9 matches the time frame of the peak in behavioral spasm intensity.

Article Snippet: Neonatal EEG Neonatal mice (P8, 9, or 10; based on minimal animal weight required to perform surgery) were anesthetized with isoflurane, surgically implanted with a custom made neonatal EEG radio telemetry head mount (Epitel/Ripple, Salt Lake City, Utah; 100× amplification) with two differential EEG electrodes placed into burr holes made symmetrically (left and right) near the anterior of the parietal bone (over the somatosensory cortex).

Techniques: Activity Assay, Disruption

Journal: Journal of NeuroEngineering and Rehabilitation

Article Title: A scoping review of eye tracking metrics used to assess visuomotor behaviours of upper limb prosthesis users

doi: 10.1186/s12984-023-01180-1

Figure Lengend Snippet: Context and key findings of included studies

Article Snippet: Hebert et al. (2019) [ ] , To determine whether different tasks performed by prosthesis users would result in different visuomotor behaviours , Head-mounted (Dikablis Professional, Ergoneers) , Percent fixation and eye latencies , Movement time and upper body range of motion , A cup transfer task involved moving two cups sequentially across a partition to two target locations then returning the cups to their starting locations. A pasta task involved moving a pasta box from a starting location on the side of the body to a centre shelf, then around a barrier to a second higher shelf, then to its starting location , The cup transfer task required more visual attention to the hand than the pasta task during reach and transport phases, likely due to the risk of spilling the contents of the cup. In both tasks, users had prolonged eye latencies and less fixation on the current target compared to a normative group.

Techniques: Control, Sequencing, Activity Assay, Activation Assay, Construct